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Prof. Dr. Karsten Krüger

Funktion:

Professor, Leitung des Arbeitsbereichs "Sport und Gesundheit"

Geschäftsführender Leiter

Telefon:

+49 511.762-5148
Fax:+49 511.762-2196
E-Mail:Karsten.kruegersportwiss.uni-hannover.de
Standort:

316 (1806)
Am Moritzwinkel 6
30167 Hannover

 

Sprechstunde:

Mo. 14:00-15:00 Uhr

In der vorlesungsfreien Zeit gelten andere Sprechzeiten.
Diese können Sie hier einsehen. 

Zur Person

Lebenslauf

  • 2017 Professor für Sport und Gesundheit an der Leibniz Universität Hannover
  • 2015-2017 Akademischer Rat, Institut für Sportwissenschaft, Justus-Liebig-Universität Gießen
  • 2015 Habilitation mit dem Titel „Immunologische Aspekte der Adaptation an Belastung und Training“, Erwerb der Bezeichnung „Privatdozent“ und der Lehrbefugnis (venia legendi) für das Fachgebiet Sportwissenschaft/Sportbiologie
  • 2011-2015 Lehrkraft für besondere Aufgaben, Institut für Sportwissenschaft, Justus-Liebig-Universität Gießen
  • 2009 Promotion zum Dr. rer. nat. zum Thema: “Mechanisms of quantitative and functional changes of lymphocytes after acute exercise”
  • 2006-2010 Wissenschaftlicher Mitarbeiter, Abteilung für Sportmedizin, Justus-Liebig-Universität Gießen
  • 2005-2006 Wissenschaftlicher Mitarbeiter, Institut für Sportmedizin, UKM-Münster

Wissenschaftliche Auszeichnungen 

  • Auszeichnung beste Examensarbeit FB Psychologie/Sportwissenschaft 2004, Münster.
  • Posterpreis, Jahrestagung der Deutschen Gesellschaft für Sportmedizin und Prävention (DGSP) 2007, Köln.
  • 2nd Place prize Early Young Career Researcher Award, International Society of Exercise and Immunolog (ISEI) Symposium 2011, Oxford, GB.
  • Vortrags-/Posterpreis auf dem DGSP Jubiläumskongress 2013, Berlin
  • Immunotools Special Award Winner 2015

Arbeitsschwerpunkte

Arbeitsbereich Sport und Gesundheit

  • Sport und Immunsystem/Entzündung
  • Sporttherapie bei internistischen Erkrankungen
  • Molekulare und zelluläre Grundlagen der trainingsinduzierter Anpassungen
  • Mechanismen anti-entzündlicher Effekte von Sport
  • Sport und Immunseneszenz

Publikationen

Stand Sommersemester 2018

Publikationen (Zeitschriftenartikel, Peer-Review)

2018

  • Alack A, Krüger K, Weiss A, Schermuly R, Frech T, Eggert M, Mooren FC. Aerobic endurance training status affects lymphocyte apoptosis sensitivity by induction of molecular genetic adaptations. Brain, Behavior, and Immunity. Accepted. 
  • Despeghel M., Krüger K, Hein-Rusinek U. Auswirkungen eines 12-wöchigen präventivmedizinisch-orientierten Minimalprogrammes auf Gewicht, Blutdruck und die gesundheitsbezogene Lebensqualität. ASU Arbeitsmedizin | Sozialmedizin | Umweltmedizin. 201, 53, 725-730. 
  • Qiu S, Bosnyák E, Treff G, Steinacker JM, Nieß A, Krüger K, Mooren FC, Zügel M, Schumann U. Acute exercise-induced irisin release in healthy adults: associations with training status and exercise mode European Journal of Sport Science. Accepted.
  • Krüger K, Seimetz S, Ringseis R, Wilhelm J, Pichl A, Couturier A, Eder K, Weissmann N, Mooren FC. Exercise training reverses inflammation and muscle wasting after smoke exposure. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. 2018, 314(3): R366-R376.
  • Madani A, Richter M, Alack K, Krüger K. Immune-regulating effects of exercise on cigarette smoke induced inflammation. Journal of Inflammation Research. 2018, 24;11:155-167. (invited review)
  • Maleki, BH, Tartibian B, Mooren, FC, Fitzgerald LZ, Krüger K, Chehrazi M, Abbas M. Low-to-moderate intensity aerobic exercise training modulates irritable bowel syndrome through antioxidative and inflammatory mechanisms in women: results of a randomized controlled trial. Cytokine. 2018, 102:18-25. 

2017

  • Krüger, K. Inflammation during Obesity – Pathophysiological Concepts and Effects of Physical Activity. Deutsche Zeitschrift für Sportmedizin. 2017, 7: 163-169. (invited review)
  • Richter MJ, Grimminger J, Krüger B, Ghofrani HA, Mooren FC, Gall H, Pilat C, Krüger K. Effects of exercise training on pulmonary hemodynamics, functional capacity and inflammation in pulmonary hypertension. Pulmonary Circulation. 2017, 1;7(1):20-37.
  • Bermon S, Castell LM, Calder PC, Bishop NC, Blomstrand E, Mooren FC, Krüger K, Kavazis AN, Quindry JC, Senchina D, Nieman DC, Gleeson M, Pyne DB, Kitic C, Close GL, Larson-Meyer DE, Marcos A, Meydani SN, Wu D, Walsh NP, Nagatomi R. Consensus Statement Immunonutrition and Exercise. Exercise Immunology Review. 2017; 23:8-50.
  • Gronau T, Krüger K, Prein P, Aszodi A, Gronau I, Iozzo RV, Mooren FC, Clausen-Schaumann H, Bertrand J, Pap T, Bruckner P, Dreier R. Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucin-rich proteoglycan decorin. Annals of Rheumatic Diseases. 2017, 76(2): 442-449.
  • Muders K, Pilat C, Deuster V, Frech T, Krüger K, Pons-Kühnemann J, Mooren FC. Effects of Traumeel (Tr14) on recovery and inflammatory immune response after repeated bouts of exercise: A double-blind RCT. European Journal of Applied Physiology. 2017, 117(3): 591-605.
  • Liu R, Fan W, Krüger K, Xiaou Y, Pilat C, Seimetz M, Ringseis R, Baumgart-Vogt E, Eder K, Weissmann N, Mooren FC. Exercise affects T cell function via modifying intracellular calcium homeoostasis. Medicine & Science in Sports & Exercise. 2017, 49(1): 29-39.
  • Pilat C, Krüger K, Frech T, Mooren FC. Comparison of exercise-induced cytokine changes in antigen stimulated whole-blood cultures and serum. Journal of Immunological Methods. 2017, 440: 58-66. 

2016

  • Krüger K, Alack K, Ringseis R, Mink K, Pfeifer E, Schinle M, Gindler K, Kimmelmann L, Walscheid R, Frech T, Eder K, Mooren FC. Apoptosis of low differentiated, highly differentiated and regulatory T cells is differently affected by high-intensity interval exercise compared to isocaloric continuous exercise. Medicine & Science in Sports & Exercise. 2016, 48(10): 2021-9.
  • Krüger K, Bredehöft J, Mooren FC, Rummel C. Strength and endurance exercise training differently affect COX-2 and mPGES expression in mouse brain independent of peripheral inflammation. Journal of Applied Physiology. 2016, 121(1): 248-54.
  • Mardare C*, Krüger K*, Liebisch G, Seimetz M, Couturier A, Ringseis R, Wilhelm J, Weissmann N, Eder K, Mooren FC. Endurance as well as resistance training affect high fat diet induced increase of ceramides, inflammasom expression and systemic inflammation in mice. Journal of Diabetes Research, 2016;2016: 4536470. *Both authors similarly contributed to the manuscript
  • Krüger K, Pilat C, Tirekoglou P, Frech T, Mooren FC. Positions- und Spielklassenspezifität anthropometrischer und konditioneller Faktoren im Männerhandball. Deutsche Zeitschrift für Sportmedizin. 2016, 6: 144-149.
  • Krüger K, Mooren FC, Pilat C. Effects of physical activity on Immunomodulation. Current Pharmaceutical Design 2016;22(24):3730-48. (invited review)
  • Meurer S, Krüger K, Mooren FC. MicroRNAs unter Einfluss körperlicher Belastung. Deutsche Zeitschrift für Sportmedizin. 2016, 2.
  • Despeghel M, Krüger K. Effects of a 12-week Minimum Program for Preventive Medical Purposes. British Journal of Medicine & Medical Research. 2016,17(1): 1-7.
  • Hajizadeh Maleki B, Tartibian B, Mooren FC, Krüger K, FitzGerald LZ, Chehrazi M. A randomized controlled trial examining the effects of 16 weeks of moderate-to-intensive cycling and honey supplementation on lymphocyte oxidative DNA damage and cytokine changes in male road cyclists. Cytokine. 2016, 88: 222-231.
  • Muders K, Pilat C, Deuster V, Frech T, Krüger K, Pons-Kühnemann J, Mooren FC. Effects of Traumeel (Tr14) on exercise-induced muscle damage response in healthy subjects: A double-blind RCT. Mediators of Inflammation. 2016;2016: 1693918. 

2015

  • Krüger K, Pilat C, Schild M, Lindner N, Frech T, Muders K, Mooren FC. Progenitor cell mobilization after exercise is related to systemic levels of G-CSF and muscle damage. Scandinavian Journal of Medicine and Science in Sports. 2015, 25(3): e283-91.
  • Krüger K, Dischereit G, Seimetz M, Wilhelm J, Weissmann N, Mooren FC. Time course of cigarette smoke-induced changes of systemic inflammation and muscle structure. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2015,15;309(2): L119-28.
  • Krüger K, Petermann C, Pilat C, Schubert E, Pons-Kühnemann J, Mooren FC. Preventive strength training improves working ergonomics during welding. International Journal of Occupational Safety and Ergonomics. 2015, 21(2):150-7.
  • Mooren FC, Krüger K. Apoptotic lymphocytes induce progenitor cell mobilization after exercise. Journal of Applied Physiology. 2015, 119(2):135-9.
  • Mooren FC, Krüger K. Exercise, Autophagy, and Apoptosis. Progress in Molecular Biology and Translational Science. 2015, 135: 407-22. (invited review)
  • Ringseis R, Eder K, Mooren FC, Krüger K. Metabolic Signals and Innate Immune Activation in Obesity and Exercise. Exercise Immunology Review. 2015, 21:58-68.
  • Schild M, Eichner G, Beiter T, Zügel M, Krumholz-Wagner I, Hudemann J, Pilat C, Krüger K, Nieß A, Steinacker JM, Mooren FC. Effects of acute endurance exercise on plasma protein profiles of endurance trained and untrained individuals over time. Mediators of Inflammation. 2016; 2016: 4851935.
  • Schild M, Ruhs A, Beiter T, Velders M, Hudemann J, Schmidt A, Krumholz I, Keller J, Eder K, Krüger K, Krüger M, Braun T, Nieß A, Steinacker J, Mooren FC. Basal and exercise induced label-free quantitative protein profiling of m. vastus lateralis in trained and untrained individuals. Journal of Proteomics. 2015, 3;122:119-32.
  • Pilat C, Frech, T, Wagner A, Krüger K, Hillebrecht A, Pons-Kühnemann J, Scheibelhut, C, Bödecker RH, Mooren FC. Effects of Traumeel Tablets on exercise induced immune response. The Scandinavian Journal of Medicine and Science in Sports. 2015, 25(4):534-42. 

2014

  • Krüger K, Klocke R, Kloster J, Nikol S, Waltenberger J, Mooren, FC. Activity of daily living is related to numbers of CD34/KDR cells and granulocyte colony-stimulating factor in patients after myocardial infarction. Journal of Applied Physiology. 2014, 1;116(5): 532-7.
  • Krüger K, Pilat C, Ueckert K, Frech T, Mooren FC. Physical performance profile of handball players is related to playing position and playing class. Journal of Strength Conditioning Research 2014, 28(1):117-25.
  • Krüger K, Kosanovic D, Schermuly RT, Mooren FC, Weissmann N, Seimetz M. Exercise in pulmonary diseases – good or bad?! An inflammatory point of view. Pulmonary Circulation. 2014, Vol. 1 Issue 2. (invited review)
  • Krüger K, Mooren FC., Eder K, Ringseis, R. Immune and Inflammatory Signaling Pathways in Exercise and Obesity. American Journal of Lifestyle Medicine. 2014, 8: 268-279. (invited review)
  • Krüger K, Mooren FC. Exercise induced leukocyte apoptosis. Exercise Immunology Review. 2014, 20:117-34.
  • Weissmann N, Peters D, Kloepping C, Krüger K, Pilat C, Katta S, Seimetz M, Ghofrani A, Schermuly R, Witzenrath M, Seeger W, Grimminger F, Mooren FC. Structural and functional prevention of hypoxia-induced pulmonary hypertension by individualized exercise training in mice. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2014, 1;306(11): L986-95.
  • Mooren FC, Viereck J, Krüger K, Thum T. Circulating microRNAs as potential biomarkers of aerobic exercise capacity. American Journal of Physiology - Heart and Circulatory Physiology. 2014, 306(4): H557-63.
  • Gutekunst K, Krüger K, August C, Diener M, Mooren FC. Acute exercise induce disorders in the gastrointestinal system in a murine model. European Journal of Applied Physiology. 2014, 114(3): 609-17. 

2013

  • Krüger K, Banisch J, Ringseis R, Gessner DK, Eder K, Seimetz M, Weissmann N, Mooren FC. Functional and muscular adaptations in a murine model of strength training. PLoS ONE. 2013, 13;8(11): e79069.
  • Khan M, Ringseis R, Mooren FC, Krüger K, Most E, Eder K. Niacin supplementation increases the number of oxidative fibers in skeletal muscle of growing pigs. BMC Veterinary Research. 2013, 9;9:177.
  • Scholz K, Kynast AM, Couturier A, Mooren FC, Krüger K, Most E, Eder K, Ringseis R. Supplementing healthy rats with a high Niacin dose has no effect on muscle fiber distribution and muscle metabolic phenotype. European Journal of Nutrition. 2014, 53(5):1229-36.
  • Khan M, Couturier A, Kubens JF, Most E,Mooren FC, Krüger K, Ringseis R, Eder K. Niacin supplementation induces type II to type I muscle fiber transition in skeletal muscle of sheep. Acta Veterinaria Scandinavia. 2013, 22, 55:85.
  • Couturier A, Ringseis R., Mooren FC, Krüger K, Most E, Eder K. Carnitin supplementation to obese zucker rats prevents obesity induced type II to Type I muscle fiber transition and favors and oxidative phenotype of muscles. Nutrition & Metabolism. 2013,10;10: 48.
  • Bobrich M, Schwabe SA, Brobeil A, Viard M, Kamm M, Mooren FC, Krüger K, Tag C, Wimmer M. PTPIP51 – a new interaction partner of the insulin receptor and PKA in adipose tissue. Journal of Obesity, 2013;2013: 476240.  

2012

  • Mooren FC, Völker K, Krüger K. Exercise delays neutrophils apoptosis by a G-CSF dependent mechanism. Journal of Applied Physiology. 2012,113(7): 1082-90.
  • Ringseis R, Rosenbaum S, Gessner D, Herges L, Mooren FC, Krüger K, Eder K. Supplementation with niacin increases PPARg-dependent gene expression and induces muscle fiber transition from glykolytic to oxidative in skeletal muscle of obese zucker rats. Journal of Nutrition. 2012, 143(2):125-31.
  • Pilat C, Krüger K, Frech T, Mooren FC. Umfang sportmedizinischer und sportwissenschaftlicher Betreuung im deutschen Spitzenhandball. Deutsche Zeitschrift für Sportmedizin. 2012, 11: 324-328.
  • Krüger K, Mooren FC. Sport, Immunsystem und rheumatologische Erkrankungen. Aktuelle Rheumatologie. 2012, 37(03): 189-195 (invited review) 

2011

  • Krüger K, Agnischock S, Lechtermann A., Tiwari S., Mishra M., Pilat C., Wagner A., Tweddell C, Gramlich I, Mooren FC. Intensive resistance exercise induces lymphocyte apoptosis via cortisol and glukocorticoid receptor dependent pathways. Journal of Applied Physiology. 2011, 110(5): 1226-32.
  • Ringseis R, Mooren FC, Keller J, Couturier A, Wen G, Hirche F, Stangl GI, Eder K, Krüger K. Regular endurance exercise improves the dimished hepatic carnitine status in mice fed a high fat diet. Molecular Nutrition and Food Research. 2011, 552: S193-202.
  • Mooren FC, Völker K, Krüger K, Golf SW, Wadepuhl M, Kraus A. Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects. A double blind placebo controlled randomized trial. Diabetes, Obesity and Metabolism. 2011,13(3): 281-4.
  • Bobrich M, Brobeil A, Mooren FC, Krüger K, Steger K, Tag C, Wimmer M. PTPIP51 interaction with PTP1b and 14-3-31ß in adipose tissue of insulin resistant mice. International Journal of Obesity. 2011, 35: 1385-94.
  • Ruscheweyh R, Willemer C, Krüger K, Duning T, Warnecke T, Sommer J, Völker K, Ho HV, Mooren F, Knecht S, Flöel A.Physical activity and memory functions: An interventional study. Neurobiology of Aging. 2011, 32(7):1304-19.   

2009

  • Krüger K, Frost S, Most E, Völker K, Pallauf J, Mooren FC. Exercise affects tissue lymphocyte apoptosis via redox-sensitive and Fas-dependent signaling pathways. American Journal of Physiology - Regulative, Integrative and Comparative Physiology. 2009, 296(5): R1518-27.
  • Flöel A, Ruscheweyh R, Krüger K, Willemer C, Winter B, Völker K, Lohmann H, Zitzmann M, Mooren F, Breitenstein C, Knecht S. Physical activity and memory functions: Are neurotrophins and cerebral gray matter volume the missing link? Neuroimage. 2009, 9(3):2756-63. 

2008

  • Krüger K, Lechtermann A, Fobker M, Völker K, Mooren FC. Exercise induced redistribution of T lymphocytes is regulated by adrenergic mechanisms. Brain, Behaviour, and Immunity. 2008, 22(3):324-38.  

2007

  • Winter B, Breitenstein C, Mooren FC, Völker K, Fobker M, Lechtermann A, Krüger K, Fromme A, Korsukewitz C, Flöel A, Knecht S. Immediate improvement of cognition after physical exercise: High impact running enhances word learning. Neurobiology of Learning and Memory. 2007, 87(4):597-609.
  • Krüger K, Mooren FC. T cell homing and exercise. Exercise Immunology Reviews. 2007, 13:37-54. (invited review) 

BÜCHER UND BUCHBEITRÄGE

  • Krüger K. Die wachsende Bedeutung immunregulatorischer Effekte von körperlicher Aktivität (Editorial). Deutsche Zeitschrift für Sportmedizin. 2017, 12: 277-279. (invited editorial)
  • Krüger K. Der stille Feind in meinem Körper. Wie chronische Entzündungen uns krank machen und was wir dagegen tun können. Scorpio-Verlag, 2017.
  • Krüger K, Schild M, Zügel M, Beiter T, Schumann U, Steinacker JM, Niess A, Mooren FC. Optimierung von Training und Wettkampf. Belastungs- und Anpassungsmanagement im Spitzensport. BISP Jahrbuch 2016.
  • Hillebrecht A, Bauer P, Frech T, Walscheid R, Linnenweber S, Wyss D, Barthelmes C, Krüger K, Willmund G, Mooren FC, Nöring R, Zeißler S. Effects of an Exercise Intervention on Metabolism and Quality of Life in Patients with Diabetes Mellitus. Advances in Ergonomic Design of Systems, Products and Processes. 2016, pp 177-187.
  • Krüger K, Mooren FC. Sporttherapie bei Spondylitis ankylosans. In. Mooren, Knapp, Reimers: Prävention und Therapie durch Sport. Elsevier Verlag, 2015, Band 3.
  • Krüger K, Mooren FC. Sport und Rheumatoide Arthritis. In. Mooren, Knapp, Reimers: Prävention und Therapie durch Sport. Elsevier Verlag, 2015, Band 3.
  • Mooren FC, Krüger K. Fitness-Handbuch für Schweißer. Abicor-Binzel, 2014.
  • Krüger K. Morbus Bechterew - Kann Sport die Entzündung regulieren? Morbus Bechterew Journal, Frühjahr 2013.
  • Krüger K. Lungensport - Rehabilitatives Training statt "nur" Üben. Luftpost. Ausgabe Frühjahr 2012.
  • Jäger J, Krüger K. (Herausgeber): Der Muskel im Sport. KVM Verlag 2012 (Fachbuch).
  • Krüger K, Mooren FC. Möglichkeiten der Trainingseffektivierung und Diagnostik im Belastungs- / Erholungszyklus. BISp-Jahrbuch Forschungsförderung 2011/12.
  • Krüger K. Lymphocytes. In: Mooren, F.C. (Herausgeber): Exercise Medicine in Health and Disease. Springer 2011.
  • Mooren FC, Pilat C, Stein B, Krüger K, Hessels J. Limitierungen der sportlichen Leistungsfähigkeit durch Störungen der gastrointestinalen Integrität. BISP Jahrbuch Forschungsförderung 2009/10.
  • Krüger K. Gesundheitsmanagement im Polizeidienst III: Der ergonomische Arbeitsplatz. Polizeispiegel. 2009, 5: 33-42.
  • Krüger K. Ernährung am Arbeitsplatz. Polizeispiegel. 2009, 4: 27-36.
  • Tunca E, Krüger K, Mooren FC. Exercise, Stem Cells and Cancer. In: Cancer and Stem Cells. Editor: Thomas Dittmar and Kurt S. Zänker. Nova Science Publishers, Inc., 2008.
  • Krüger K. Gesundheitsmanagement im Polizeidienst. Polizeispiegel. 2007, 5: 16-25. 

Weitere Publikationen

Zitationen